Vardenafil Raw Material

Vardenafil Raw Material

Vardenafil is used to treat erectile dysfunction. This medication is a type 5 phosphodiesterase (PDE5) inhibitor. Oral administration effectively improves erection quality and duration, enhancing the success rate of sexual activity in male patients with erectile dysfunction. The initiation and maintenance of penile erection are related to the relaxation of cavernous smooth muscle cells, with cyclic guanosine monophosphate (cGMP) serving as the mediator for cavernous smooth muscle relaxation
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Description
Technical Parameters

English Name: Vardenafil
Chinese Alternate Names: Vardenafil Hydrochloride; Vardenafil Dihydrochloride
English name: Vardenafil
English name: Vardenafil dihydrochloride
CAS No.: 224789-15-5
Molecular formula: C29H40N6O11S
Molecular weight: 680.72600
Exact mass: 680.24800
PSA:253.41000
LogP:1.77850 [1]
Pharmacological agents related to vardenafil

Product Usage
Vardenafil is currently the latest medication in the field of erectile dysfunction (ED) treatment worldwide. It was developed by Bayer and GlaxoSmithKline in Germany after years of research and development. It works by inhibiting type 5 phosphodiesterase (PDE-5). Compared with sildenafil (Viagra), it has the following advantages: it requires less dosage, only 20mg (sildenafil requires 120mg-150mg). Quick onset time, taking effect within 15 to 30 minutes. The side effects are minimal, but due to individual differences, less than 2% of people may still experience mild headaches. The characteristic of being soluble in water and ethanol makes it an ideal raw material for making aphrodisiac alcoholic beverages, soft capsules, and oral liquids. The duration can reach more than 6 hours, and the launch of Vardenafil has made the current internationally advanced aphrodisiac raw materials into three: Sildenafil (brand name: Viagra), Tadalafil (brand name: Sildenafil Cialis), and Vardenafil (brand name: Alida). Vardenafil was approved by the US FDA in August 2003 and has also been launched in the European Union. Vardenafil's complete solubility in water and ethanol makes it the most ideal and preferred raw material for the production of health enhancing and aphrodisiac wines, oral liquids, beverages, and soft capsules. Additionally, it has been favored by other high-end aphrodisiac product manufacturers for its minimal usage, fast onset time, and high safety. Numerous clinical studies have shown that Vardenafil hydrochloride, as a new generation phosphodiesterase 5 (PDE5) inhibitor, has the characteristics of strong efficacy, high selectivity, and good tolerability. Its emergence has brought new options for the treatment of erectile dysfunction (ED).

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