Density: 1.51 g/cm³
Melting point: 298-300°C
Boiling point: 679.1°C
Flash point: 364.5°C
logP: 1.43
Refractive index: 1.758
The company mainly operates in raw materials for female weight loss and male health supplements.
Rapidly absorbed after oral administration, reaching the mean maximum observed plasma concentration (Cmax) at a median time of 2 hours after dosing. The absolute bioavailability after oral administration of this drug has not been determined. The rate and extent of absorption of tadalafil are not affected by food, so this product can be taken with or without food. The time of administration (morning or evening) has no clinically significant effect on the rate and extent of absorption, with an average volume of distribution of approximately 63 liters, indicating that tadalafil distributes into tissues. At therapeutic concentrations, 94% of tadalafil in plasma is protein-bound. Protein binding is not affected by impaired renal function. In healthy subjects, the mean oral clearance of tadalafil is 2.5 L/hr, and the mean half-life is 17.5 hours. Tadalafil is mainly excreted as inactive metabolites, primarily via feces (approximately 61% of the dose), and to a lesser extent via urine (approximately 36% of the dose).
