Tadalafil: CAS No. 171596-29-5. Tadalafil is a selective and reversible inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase 5 (PDE5). When sexual stimulation leads to the local release of nitric oxide, PDE5 is inhibited by tadalafil, increasing cGMP levels in the corpora cavernosa of the penis. This results in smooth muscle relaxation, increased blood flow to the penile tissue, and erection. Without sexual stimulation, the drug may not be effective.
Dosage and Administration
The recommended dose is 30 mg, taken before sexual activity, regardless of food intake. If the effect of 30 mg is not significant, 50 mg can be taken, at least 30 minutes before sexual activity.
The maximum frequency of administration is once daily.
Product Specifications and Parameters
- Chinese Name: Tadalafil;
- CAS No. 171596-29-5;
- Chemical Formula: C22H19N3O4;
- Molecular Weight: 389.404;
- Melting Point: 298 to 300 ℃;
- Appearance: White powder.
- Testing Method: High-performance liquid chromatography (HPS)
- Standard: USP (United States Patent and Trademark Office)
Product Development and Application
Tadalafil can be used in tablet, capsule, and alcoholic beverage forms for erectile dysfunction and pulmonary hypertension. It takes effect approximately one hour after administration and lasts for 48 to 60 hours. No side effects.
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